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  1. #1
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    Default Tyrokinase Inhibitors

    Hola a Todos...

    Im translating a handout about Skin Rashes, it is talking about Epidermal Growth Factor Receptor (EGFR). On of the Inhiditors is Tyrokinase Inhibitors. I have no idea what it could be in spanish... I have been trying to do some research but im not coming up with anything.

    Auxilio!!!
    Muchas Gracias,

    Stephanie

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    Senior Member Guadalupe's Avatar
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    Default Re: Tyrokinase Inhibitors

    Hi, Stephanie!

    I think these are "inhibidores de la tirosinasa", since I assume "tyrokinase" is another (less common) spelling for "tyrosinase".

    La tirosinasa (monofenol monooxigenasa) (EC 1.14.18.1; número CAS: 9002-10-2) es una enzima que cataliza la oxidación de fenoles (como la tirosina) y está extendida en plantas y animales. La tirosinasa es una enzima cuprífera presente en tejidos de plantas y animales que cataliza la producción de melanina y otros pigmentos de la tirosina por oxidación, como el ennegrecimiento de una patata pelada o cortada expuesta al aire.
    Source: es.wikipedia.org/wiki/Tirosinasa

    Hope it helps
    Guadalupe

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    Default Re: Tyrokinase Inhibitors

    Gracias Guadalupe,
    That whats I thought too, i think they misspled it wrong on the english document!
    Gracias, que tengan buen dia!
    Stephanie

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    Senior Member Veronica's Avatar
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    Default Re: Tyrokinase Inhibitors

    Hi all!

    I think "tyrokinase" is a typo too. It's tyrosinase.

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    Default Re: Tyrokinase Inhibitors

    Hi Stephanie,

    This article talks about EGFR and tyrosine kinase:
    http://www.expert-reviews.com/doi/abs/10.1586/14737140.4.1.5

    I think the tyrokinase is another way to write tyrosine kinase.
    Reference #18 at the end of this article uses tyrokinase in the same context as tyrosine kinase:
    http://clincancerres.aacrjournals.org/cgi/reprint/10/12/4233S

    The tyrosine kinase has a very different function than the tyrosinase:
    http://en.wikipedia.org/wiki/Tyrosine_kinase

    I think the translation should be tirosina quinasa or tirosina kinasa.
    See the last 2 parragraphs in this page:
    http://temasdebioquimica.wordpress.com/2008/07/13/las-quinasas-o-kinasas/

    This is a long answer, but I hope it helps.

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